Thursday, June 5, 2014

An example of my previous post on biomimetics

Shrimp key to new material that can build tougher jets http://timesofindia.indiatimes.com/home/science/Shrimp-key-to-new-material-that-can-build-tougher-jets/articleshow/34134244.cms via @timesofindia

Tuesday, March 18, 2014

Biomimetics

Welcome to the world of biomimetics!
Wondering what's it all about?
Everything is right in front of you.
Nature is the supreme driving force of all that exists. And will ever exist. But we are humans. We have humanity.we love nurture nourish and together we flourish.
What then is the divider between us and every one else? It's human nature to be curious, to explore, to take calculated risks, to unearth the truth, and to know what lies beneath.
Human evolution skated on the roller blades of curiosity. Its human nature to tinker with things. To tamper things and hack or tweak as per our own fancy. But where is this leading us ? Amidst the technology, and the world wide web, the internet era has pushed the earth into a new epoch.'Anthropocoene' whether we like it or not, we have altered everything around us as per our own whims and fancies !
But what could be the holy grail of this vast design? Intrigued? You better be.cos that's what makes you human! Nature is the best architect. And the best teacher.
And here comes the word. Biomimetics.
Mimicry of nature, them answer to most of our questions is right in front of our very own eyes!
Biomimetics is the science of mimicking nature. And it's marriage with technology.
Couldn't have been a better couple right?
From designing planes like birds, to designing fluidic cars. Combining the Master plan of nature and adding our own flavour to it.
The applications are endless! We can now create tiny bots to eradicate mosquitoes, have micro drones or bugs attached with sensors and cameras for spying. Talk of a bionic fish which will swim in water like a real fish but at the same time relay information in real time! About the temperature, any seismic activity or any untoward incidents.
The biomimetic rats may one day be used for mining or even oil drilling. The robotic powered earthworm could help improve the crops. We could even have ants like mini soldiers. Imagine bees with sensors cameras and micro weapons .which sting and vaccinate all animals or who knows even humans! We could have snake trains, which could traverse any kind of terrain without needing tracks! Think weather forecasting in real time by these biomimetic devices.think fly like bots informing u which is the shortest route to reach ur destination or the timings of the next movie show ! Possibilities are endless.and outcomes too! Now bring nanotechnology into the picture n it becomes a potboiler! Welcome . with open arms, the world of biomimetics! Where messages used to be sent through birds which have now become virtual (twitter)
Biomimetics is the future n here to stay.
You never know which way leads us to our  singularity. Playing God  it seems is the newest human passion!

Tuesday, February 11, 2014

I am strong

In the moon light
In the day light
Struggle to get on

And you know me
Understand me
You will make me strong

You will make me strong
You will make me strong

Look at me
Here I am
Reaching for your arms again

Of all the hurt and all the pain
Get back on my feet again

Hear me sying
Feel the crying
I am not alone

Cause' you see me
Want to be me
Melancholy soul

Melancholy soul

Look at me
Here I am
Reaching for your arms again

Of all the hurt
And all the pain
Get back on my feet again

Diez
Nueve
Ocho
Siete
Seis
Cinco
Cuatro
Tres
Dos
Un..

There is no fear
There is peace here
I have found a home

Look at me
Here I am (I am strong when I'm in love)
Reaching for your arms again

Of all the hurt and all the pain (I am strong when I'm in love)
Get back on my feet again

I am strong when I'm in love
I am strong when I'm in love
I am strong when I'm in love

Look at me
Here I am
Reaching for your arms again

Of all the hurt
And all the pain
Get back on my feet again

Look at me
Here I am (I am strong when I'm in love)
Reaching for your arms again

Of all the hurt and all the pain (I am strong when I'm in love)
Get back on my feet again

I am strong when I'm in love
I am strong when I'm in love
I am strong when I'm in love

Wednesday, January 29, 2014

Ecstatic Epilepsy

This one is dedicated to my Grandfather.and GRAND ,he was..

Epilepsy is the disease in which seizures occur (jhatke aana)
Never had I thought It will change my perception of things.
It began when as a child, I used to sit in religious rituals watching my grandfather, as after all the conondrum of bells, the smoke from the fire which filled the entire room.
He would suddenly go in a trance like state and blurt out prophecies in an altogether different tone of voice, and as a child I saw many such intriguing cases.
After having understood the basic mechanisms and effects of a seizure, (thanks to my residency, ) I came to think of it as a phenomenon.
The human Brain is a very highly differentiated organ, critical for survival.
But alongside our basic life processes, evolution gifted humans with a brain so powerful, and so potent, it could actually shake up things around.
We Humans have changed everything around us as per our convenience.
But with great power, comes great responsibility...
We are all imperfect, and the brain too has its own set of issues.
The human brain is like a gamut of multiple core processors, all synchronous and interconnected through synapses.
There's a region for controlling everything. From feeling hungry to feeling angry, from depression to extacy..
You could liken it to a fuse.beyond certain current, the fuse melts to avoid damage to the machine.
Sadly,or gladly, we were not blessed with any such thing as a fuse.
When the neurons discharge excessively, the sentient gets a seizure.
Different areas of the brain could be involved in this 'sparkly activity' which is like a party gone wrong for the brain..seizures from each region have typical features as we know.Temporal lobe, for example, would cause a person to enter altered mental states.If the region responsible for peace, contentment. Happiness is involved, its an altogether different story.
Experts say the anterior cingulate gyrus is found to be involved in such kind of 'ecstatic seizure'
It was a chance discovery which opened up many closed doors..
It could be possible that all those shaman's, all those ppl who give a message from the other side, the paranormal, the superhuman and the divine, could have this sort of epilepsy, or some, may even be using the bells, the lights, the noise,the chants to get that ecstatic seizure ,which opens up a window into the other side, prophecies, sermons, prediction, even messages from the 'other' side.
So after much reading and deep thought I concluded that it must be some sort of ecstatic seizures which happen to people amongst all rituals.
Finally, I got the answer to my question.
Now what altered states lead to, how the predictions work, how the messages from the other side are conveyed is still a matter of contention. And , we need to think more about that.maybe in the next blog !
Still interested? Read on..
Relevant article :

http://www.newscientist.com/article/mg22129531.000-diagnosing-dostoevsky-understanding-ecstatic-seizures.html#.UujoCZ-3TqB

Tuesday, January 21, 2014

An Interesting case of TRUCUSPID VALVE TEAR in a patient with RHD

Patient was. 30/M, known RHD, presented with
Acute onset SOB GR IV NYHA
chest pain
Palpitations.
On clinical examination,
Pulse 120bpm regular rhythm (sinus tachycardia)
BP 90/60 mm Hg
JVP FULL
B/L minimal pitting pedal edema
CVS
apex L 5th ICS inside MCL tapping type
PALPABLE THRILL AT MITRAL AREA
DIASTOLIC SHOCK (palpable P2) at PA
Palpable thrill at tricuspid area
LOUD P2 at Pulmonary area,
SOFT S1 at Mitral area

MDM GR IV at MA ,low pitched,rumbling murmur, best heard with bell in Left lateral position at expiration.

PSM GR IV at TA ,high pitched , best heard in supine position at end expiration

EDM at NAA Gr II high pitched, best heard I'm sitting position at end expiration.

ECG FINDINGS
Bi Atrial enlargement…
RV +

ECHOCARDIOGRAPHY FINDINGS
Heavily calcified Mitral Valve leaflets
Severe MS
MVA 0.66 cm ²( PHT method)
0.82cm ² ( PSAX Planimetry)
Grossly dilated RA &RV
RA volume approx 300 -350,ml
(77x70x71)
RVID basal Diameter 41mm
And now the most interesting finding
Severe TR WITH  'Double ' JET
I tried to see if the jets were arising fromthe same place, but on close observation  and different planes & views, it was clear that both jets were different.
One jet arised from the normal TRICUSPID INFLOW while the other jet originated somewhere laterally .
The velocities of both these regurgitant jets were different.
Central jet being 4.5 m/s
While lateral jet 2.6m/s
They both gave a separate distinct jets visible on Color Doppler.
there was also mild PULMONARY REGURGITATION,
Mild MITRAL REGURGITATION
MILD AORTIC STENOSIS WITH MILD AORTIC INCOMPETENCE.

thankfully there were no clots.
FINAL DIAGNOSIS :
VHD
severe MS (?CRITICAL) with heavily calcified both leaflets
mild MR
Grossly dilated RA RV
SEV TR WITH DOUBLE JET (? TRICUSPID LEAFLET PERFORATION)
SEV PAH
(PASP 75 mm Hg)
Mild AS with AR.
Probably Rheumatic in origin

An interesting case of ?RV CYST ?Pulmonary Embolism

Patient is a 48yr old female , who presented to us with c/o SOB GRIII /IV NYHA
cough
Low grade fever
swelling all over body
since 8 days
She was treated at various hospitals for her condition diagnosed from LRTI to pericardial effusion.
Clinically she had tachycardia, BP was 100/70
Pitting pedal edema
Full JVP
CVS
APEX L 5TH ICS INSIDE MCL
PROMINENT EPIGASTRIC N SUPRASTERNAL PULSATIONS

PALPABLE P2
Loud P2
PSM GR III at TA
RS
trachea central
B/L crepts IMA ISA L>R

ECG findings :
P pulmonale in lead II(RAE)
right Axis deviation
R positivity in V1 V2
(RVH)
incomplete RBBB

I performed a bedside ECHOCARDIOGRAPHY
WITH FOLLOWING FINDINGS

DILATED RA RV
RVID 38mm
Severe TR
TR Vmax 3.6 m/s
Tr Max PG 56 mm Hg
Mild PR
CLOT in RA Appendage
And CLOT IN RV APEX (15-20cc each)
DILATED IVC (18.5mm)

Since ECHO was bedside it remains to be checked if there was an ASD or not.(on a better machine maybe)

patient was started on Anticoagulants immediately with target INR 2.5-3.5.

Pulmonary embolism is often missed out on routine diagnosis.
The triad of Cough ,Shortness of breath , Hypotension must be kept in mind for every patient with unexplained symptoms.
This patient had cardio megaly on x ray
And poor R progression inECG
She was misdiagnosed as CAD n LRTI
In this case patient presented when she developed CCF secondary to Right sided failure.
So moral of the story : Always think of PULMONARY EMBOLISM whenever any pt presents with unexplained cough DYSPNEA .
Corelation of CLINICAL FINDINGS, ECG AND ECHO ARE A MUST.
Images attached.
Comments n queries most welcome..




Update : 22/01/2014

Cardiologist opinion is that its a RV Cyst n not a clot.

Were searching for cysts in other areas

Monday, January 20, 2014

Roadmap of Life

Step 1 : Formulate
Step 2 : Plan
Step 3 : Overview resources
Step 4 : Chart paths
Step 5: Implement
Step 6 : Finalize
Step 7 : Modify, Improvise and Optimize